細(xì)胞名稱

人膀胱癌細(xì)胞SW1710

貨物編碼

BFN60811444

產(chǎn)品規(guī)格

T25培養(yǎng)瓶x1

1.5ml凍存管x2

細(xì)胞數(shù)量

1x10^6

1x10^6

保存溫度

37℃

-198℃

運(yùn)輸方式

常溫保溫運(yùn)輸

干冰運(yùn)輸

安全等級(jí)

1

用途限制

僅供科研   3類

培養(yǎng)體系

DMEM(HYCLONE SH30022.01)+10%FBS+1%三抗

培養(yǎng)溫度

37℃

二氧化碳濃度

5%

簡(jiǎn)介

人膀胱癌細(xì)胞SW1710取自84歲女性供體

注釋

Part of: BLA-40 bladder carcinoma cell line panel.

Part of: Cancer Cell Line Encyclopedia (CCLE) project.

Part of: COSMIC cell lines project.

Part of: UBC-40 urothelial bladder cancer cell line index.

From: Scott and White Clinic; Temple; USA.

Doubling time: ~25-32 hours (DSMZ).

Microsatellite instability: Stable (MSS) (Sanger).

Omics: CNV analysis.

Omics: Deep exome analysis.

Omics: Deep RNAseq analysis.

Omics: DNA methylation analysis.

Omics: SNP array analysis.

Omics: Transcriptome analysis.

基因突變

TERT c.228C>T (-124C>T); in promoter (PubMed=24035680).

HLA信息

STR信息

Amelogenin X

CSF1PO 11,12

D5S818 12

D7S820 8,11

D13S317 12

D16S539 8,11

TH01 7,10 (Cosmic-CLP)

 7,8,9.3 (DSMZ)

 7,9.3 (PubMed=27270441)

TPOX 9,11

vWA 16,17

參考文獻(xiàn)

PubMed=27270441; DOI=10.1038/onc.2016.172

 Nickerson M.L., Witte N., Im K.M., Turan S., Owens C., Misner K., Tsang S.X., Cai Z., Wu S., Dean M., Costello J.C., Theodorescu D.

 Molecular analysis of urothelial cancer cell lines for modeling tumor biology and drug response.

 Oncogene 36:35-46(2017)

PubMed=29732388; DOI=10.3233/BLC-180167

 Zuiverloon T.C.M., de Jong F.C., Costello J.C., Theodorescu D.

 Systematic review: characteristics and preclinical uses of bladder cancer cell lines.

 Bladder Cancer 4:169-183(2018)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747

 Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.

 An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.

 Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3

 Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.

 Next-generation characterization of the Cancer Cell Line Encyclopedia.

 Nature 569:503-508(2019)